Both Annapurna base camp and Everest base camp lie in the Himalayan region of Nepal. While Annapurna base camp is situated on the western region, Everest base camp lies on the eastern flanks. Annapurna base camp is located at an altitude of 4,130m / 13,550 feet while Everest base camp stands at an altitude of 5,364m / 17,598 feet. The elevation difference between the two is more than 4000 feet which means that the oxygen content in the air is less in Everest base camp. Obviously the risk of altitude sickness is much higher in Everest base camp and on any given day, it is much colder than Annapurna base camp.